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Here are several games to keep an eye on, and why they could matter more than your average Sunday.

Matchup Why It Matters Key Storylines
Seattle Seahawks @ Arizona Cardinals (TNF) Division rivalry, early season momentum. The Seahawks are slight favorites. Can Seattle exploit Arizona’s defensive weaknesses? How the QB(s) perform under the lights.
Vikings @ Steelers (International Series in Dublin) The novelty adds pressure; both teams are just 2-1. A win here could set the tone. Vikings’ offense vs. Steelers’ defense; how will travel / environment affect both squads?
Bills vs. Saints Buffalo is heavily favored; this could be another statement game for the upper-tier AFC East. Saints are winless; can they avoid a blowout? Bills will test their consistency — can their offense and secondary both show up?
Chargers vs. Giants Chargers are undefeated; Giants are winless. Testing whether LA can keep up the early dominance or if NYG can steal a morale-boosting win. How Justin Herbert manages pressure, and can the Giants’ offense spark something (especially in the red zone)?
Eagles vs. Buccaneers Both teams are 3-0 (or close to it) — going in, neither wants to drop their first. Big NFC implications early. Eagles’ run defense has been flagged; how will they handle TB’s offense? Also, resilience in close games will be important.
Cleveland Browns vs. Detroit Lions Detroit looks dangerous on offense; Cleveland is trying to recover momentum. Browns opened as large underdogs here. Can Cleveland’s defense keep pace? Will Detroit keep feeding their strengths (rush + explosive plays)?
Packers @ Cowboys (Sunday Night) Big NFC rivalry. And added intrigue because of Micah Parsons’ trade, injuries, etc. Packers need to show they can win away from home; Cowboys may be without key players.
Jets @ Dolphins (Monday Night) AFC East divisional game, and both teams need something to spark momentum. Especially Miami, which is 0-3. Can the Dolphins’ offense get going? Can the Jets defend enough to force mistakes and exploit Miami’s weaknesses?
Broncos vs. Bengals (Monday Night) High stakes in the AFC, especially if Bengals want to stop slipping, and Broncos want to prove they can compete in tight games. How well the Broncos’ defense plays under pressure / late‐game situations.

🔍 What to Watch

  • Quarterback performance under pressure: There are several matchups where QBs are either under pressure (giants dealing with injuries, teams traveling, having to chase the game) or expected to produce.

  • Injuries & depth: Chiefs, Cowboys, others have injuries that could materially affect performance. Keeping tabs on status of key players (esp. OL, WR, pass rushers) is critical.

  • Defensive consistency: Teams like the Eagles, Saints, Browns — their defensive performance could determine outcomes in many matchups. Especially 3rd down success, turnovers, red-zone stops.

  • Momentum & confidence: Early undefeated teams vs. win-struggling squads (Chargers vs. Giants, Dolphins, Saints) often are mental as well as physical. How teams respond to adversity will matter.