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1. Buffalo Bills vs. Miami Dolphins (Thursday Night Football)

  • The Bills are 2-0, coming off a solid win over the Jets, while the Dolphins are 0-2.

  • Buffalo is a heavy favorite (≈ -12.5) and expected to lean on their offense and establish control early.

  • Look for whether Miami can use their run game to offset Buffalo’s pass rush and pressure. Also, whether the Bills’ defense can limit Miami big-plays. This could be a litmus test for whether Buffalo is as dominant as early stats suggest.

2. Los Angeles Rams @ Philadelphia Eagles

  • Both teams are undefeated through two and this is a rematch of last season’s NFC Divisional Round. Philly is a slight favorite.

  • Key battle: Rams’ receivers (Davante Adams, Puka Nacua) vs. Eagles’ secondary (Adoree’ Jackson, etc.). Also interesting will be how the Eagles’ offense looks — are they fully clicking yet?

  • Also, the lines suggest a moderate over/under, meaning analysts are expecting some scoring, though these two defenses can be capable.

3. Green Bay Packers @ Cleveland Browns

  • The Packers are getting some love from simulation models. They’re expected to cover comfortably — Green Bay has shown strong defense in the first two weeks.

  • Browns’ offense has been shaky, especially with questions around Joe Flacco’s efficiency. If Green Bay can force turnovers and limit big plays, this could be a lopsided affair.

4. Houston Texans @ Jacksonville Jaguars

  • A tight spread, and predictions favor Houston slightly. Texans have impressed defensively, especially with their pass rush rates. Jacksonville has some questions at quarterback and receiver.

  • This game could be pivotal in the AFC South — early wins matter, especially when the division could come down to tiebreakers.

5. Kansas City Chiefs vs. New York Giants (Sunday Night)

  • The Chiefs are 0-2, which is concerning given their recent history, but this is an opportunity to rebound. The Giants are also winless.

  • Key storyline: Are the Chiefs’ offense and defense clicking yet? If they stumble again, questions will rise about whether this is just early-season noise or a real issue. For the Giants, this is a chance to gain traction in a tough division.

6. Detroit Lions @ Baltimore Ravens (Monday Night Football)

  • Big stage, big expectations. Baltimore is favored by around 5-6 points.

  • The Lions showed they can score in bulk (Week 2 vs. Bears), but Ravens bring a strong home field advantage and defensive identity. The Lions’ offensive line and ability to protect their QB will be under scrutiny. Ravens will look to control the clock and impose their physicality.


Other Notables

  • Saints vs. Seahawks: Seattle is a 7-point favorite over the Saints. New Orleans has looked vulnerable, but they still present intrigue, especially defensively.

  • Falcons vs. Panthers: Early divisional game. Falcons may be slight favorites. Always interesting to monitor as both NFC South teams try to avoid falling behind early.